HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone → HCID 66716741, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone | HCID 66715111 | — |
| Reactant | HCID 66715805 | HCID 66715805 | — |
| Product | HCID 66716741 | HCID 66716741 | 81.4% |
Reaction Steps
Following General procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (311 mg, 1 mmol) was reacted with tert-butyl 1-(5-aminopyrimidin-2-yl)piperidin-3-ylcarbamate (440 mg, 1.5 mmol) to afford the desired product (462 mg, 80%) as a yellow solid: ESI MS m/z 567 [C27H31BrN6O3+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-908a65d969004533b97ac7c652e751c1 |
| Source note | uspto-grants-2015_09 |