HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone → HCID 86692881, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone | HCID 66715111 | — |
| Reactant | (S)-tert-butyl 1-(5-aminopyridin-2-yl)piperidin-3-ylcarbamate | HCID 66715841 | — |
| Product | HCID 86692881 | HCID 86692881 | 93% |
Reaction Steps
Following General procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (311 mg, 1 mmol) was reacted with (S)-tert-butyl 1-(5-aminopyridin-2-yl)piperidin-3-ylcarbamate (439 mg, 1.5 mmol) to afford the desired product (527 mg, 93%) as a yellow solid: ESI MS m/z 566 [C28H32BrN5O3+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-7660bbfced8245d7bd4defdb4218d2f7 |
| Source note | uspto-grants-2015_09 |