HRID2271628

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID66715111

未命名化合物

结构：CC(C)(C)OC(=O)N[C@@H]1CCCN(c2ccc(N)cn2)C1

HCID66715874

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N[C@@H]1CCCN(c2ccc(Nc3c(C(=O)C4CC4)cnc4ccc(Br)cc34)cn2)C1

HCID86692882

未命名化合物

收率 91.1%

PROCEDURE

实验过程

Following General procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (311 mg, 1 mmol) was reacted with (R)-tert-butyl 1-(5-aminopyridin-2-yl)piperidin-3-ylcarbamate (439 mg, 1.5 mmol) to afford the desired product (516 mg, 91%) as a yellow solid:: ESI MS m/z 566 [C28H32BrN5O3+H]+.