HRID2271629

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID53470939

tert-Butyl [1-(5-aminopyridin-2-yl)pyrrolidin-3-yl]carbamate

C14H22N4O2

HCID66715111

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)NC1CCN(c2ccc(Nc3c(C(=O)C4CC4)cnc4ccc(Br)cc34)cn2)C1

HCID86692883

未命名化合物

收率 88.3%

PROCEDURE

实验过程

Following General procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (311 mg, 1 mmol) was reacted with tert-butyl 1-(5-aminopyridin-2-yl)pyrrolidin-3-ylcarbamate (417 mg, 1.5 mmol) to afford the desired product (488 mg, 88%) as a yellow solid: ESI MS m/z 552 [C27H30BrN5O3+H]+.