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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2271630Generated: November 1, 2026

(6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone → HCID 86692884, compound

https://huagongshe.com/reaction/2271630

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanoneHCID 66715111—
ReactantHCID 86692877HCID 86692877—
ProductHCID 86692884HCID 8669288461%

Reaction Steps

Following General procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (311 mg, 1 mmol) was reacted with tert-butyl 1-(5-aminopyrimidin-2-yl)pyrrolidin-3-ylcarbamate (418 mg, 1.5 mmol) to afford the desired product (336 mg, 61%) as a yellow solid: ESI MS m/z 553 [C26H29BrN6O3+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09120749B2
Source datasetuspto-grants-2015_09
ORD IDord-4d929a7b16ce498992a30de1975b4e86
Source noteuspto-grants-2015_09