HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-[3-(Dimethylamino)-1-pyrrolidinyl]-3-pyridinamine → HCID 66715218, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-[3-(Dimethylamino)-1-pyrrolidinyl]-3-pyridinamine | HCID 21105670 | — |
| Reactant | (6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone | HCID 66715111 | — |
| Product | HCID 66715218 | HCID 66715218 | 71.2% |
Reaction Steps
Following General procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (311 mg, 1 mmol) was reacted with 6-(3-(dimethylamino)pyrrolidin-1-yl)pyridin-3-amine (309 mg, 1.5 mmol) to afford the desired product (342 mg, 71%) as a yellow solid: ESI MS m/z 480 [C24H26BrN5O+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-43d7df38dd374c9f8b2ab783edf5c978 |
| Source note | uspto-grants-2015_09 |