HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone → HCID 86692887, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone | HCID 66715111 | — |
| Reactant | HCID 86692878 | HCID 86692878 | — |
| Product | HCID 86692887 | HCID 86692887 | 75% |
Reaction Steps
Following General procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (278 mg, 0.89 mmol) was reacted with (R)-4-(3-fluoropyrrolidin-1-yl)cyclohexanamine (200 mg, 1.1 mmol) to afford the desired product (307 mg, 75%) as a yellow solid: ESI MS m/z 460 [C23H27BrFN3O+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-5fc1a50274644afa8d84ccc60bc641bd |
| Source note | uspto-grants-2015_09 |