HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone → HCID 86692888, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone | HCID 66715111 | — |
| Reactant | HCID 66715482 | HCID 66715482 | — |
| Product | HCID 86692888 | HCID 86692888 | 46% |
Reaction Steps
Following General procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (311 mg, 1 mmol) was reacted with 4-(3,3-difluoropyrrolidin-1-yl)cyclohexanamine (306 mg, 1.5 mmol) to afford the desired product (218 mg, 46%) as a yellow solid: ESI MS m/z 478 [C23H26BrF2N3O+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-e998876ea15c4fab8d5b857bc4f56970 |
| Source note | uspto-grants-2015_09 |