HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone → HCID 86692890, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone | HCID 66715111 | — |
| Reactant | [1-(4-Amino-phenyl)-1-methyl-ethyl]-carbamic acid tert-butyl ester | HCID 68092215 | — |
| Product | HCID 86692890 | HCID 86692890 | 71.8% |
Reaction Steps
Following general procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (347 mg, 1.12 mmol) was reacted with tert-butyl 2-(4-aminophenyl)propan-2-ylcarbamate (420 mg, 1.68 mmol) to afford the desired product (422 mg, 63%) as a yellow solid: ESI MS m/z 524 [C27H30BrN3O3+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-727167d40dfd49c9881539fbcba61212 |
| Source note | uspto-grants-2015_09 |