HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Cyanopyrimidine-5-boronic acid pinacol ester → HCID 178454019, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Cyanopyrimidine-5-boronic acid pinacol ester | HCID 16414276 | — |
| Reactant | HCID 178454009 | HCID 178454009 | — |
| Product | HCID 178454019 | HCID 178454019 | 101.4% |
Reaction Steps
Following general procedure D, tert-butyl trans-4-[6-bromo-3-(cyclopropanecarbonyl)quinolin-4-ylamino]cyclohexylcarbamate (49 mg, 0.100 mmol) was reacted with 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2-carbonitrile (46 mg, 0.200 mmol) to afford the crude product (52 mg): ESI MS m/z 513 [C29H32N6O3+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-e9724492318147ed9bc91068fedb6c41 |
| Source note | uspto-grants-2015_09 |