HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Cyanothiophene-2-boronic acid → HCID 178454011, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Cyanothiophene-2-boronic acid | HCID 4198743 | — |
| Reactant | HCID 178454009 | HCID 178454009 | — |
| Product | HCID 178454011 | HCID 178454011 | 47% |
Reaction Steps
Following general procedure D, tert-butyl trans-4-[6-bromo-3-(cyclopropanecarbonyl)quinolin-4-ylamino]cyclohexylcarbamate (49 mg, 0.100 mmol) was reacted with 5-cyanothiophen-2-ylboronic acid (31 mg, 0.200 mmol) to afford the desired product (24 mg, 47%) as a brown solid: ESI MS m/z 517 [C29H32N4O3S+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-ffd221b4c9dd4b96be78df0b367ad8a6 |
| Source note | uspto-grants-2015_09 |