huagongshe.com
HRID2271696

反应详情

EQUATION

反应方程式

HRID 2271696 的结构方程式

REACTANTS

反应物

2
结构：OB(O)c1ccncc1
HCID2734379

Pyridine-4-boronic acid

C5H6BNO2

结构：CC(C)C(=O)c1cnc2ccc(Br)cc2c1N[C@H]1CC[C@H](NC(=O)OC(C)(C)C)CC1
HCID178450270

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N[C@H]1CC[C@H](Nc2c(C(=O)C3CC3)cnc3ccc(-c4ccncc4)cc23)CC1
HCID178454018

未命名化合物

收率 102.8%

PROCEDURE

实验过程

Following general procedure D, tert-butyl trans-4-(6-bromo-3-isobutyrylquinolin-4-ylamino)cyclohexylcarbamate (49 mg, 0.100 mmol) was reacted with pyridin-4-ylboronic acid (25 mg, 0.200 mmol) to afford the crude product (50 mg) as an off-white solid: ESI MS m/z 487 [C29H34N4O3+H]+.