huagongshe.com
HRID2271697

反应详情

EQUATION

反应方程式

HRID 2271697 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2cn[nH]c2)OC1(C)C
HCID2774010

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

C9H15BN2O2

结构：CC(C)C(=O)c1cnc2ccc(Br)cc2c1N[C@H]1CC[C@H](NC(=O)OC(C)(C)C)CC1
HCID178450270

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N[C@H]1CC[C@H](Nc2c(C(=O)C3CC3)cnc3ccc(-c4cn[nH]c4)cc23)CC1
HCID178454020

未命名化合物

收率 36%

PROCEDURE

实验过程

Following general procedure D, tert-butyl trans-4-(6-bromo-3-isobutyrylquinolin-4-ylamino)cyclohexylcarbamate (49 mg, 0.100 mmol) was reacted with 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (39 mg, 0.200 mmol) to afford the desired product (17 mg, 36%) as an off-white solid: ESI MS m/z 476 [C27H33N5O3+H]+.