HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol → HCID 178454016, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol | HCID 57655406 | — |
| Reactant | HCID 178454008 | HCID 178454008 | — |
| Product | HCID 178454016 | HCID 178454016 | 86.2% |
Reaction Steps
Following general procedure F, tert-butyl cis-4-[6-bromo-3-(cyclopropanecarbonyl)quinolin-4-ylamino]cyclohexylcarbamate (54 mg, 0.110 mmol) was reacted with 2,6-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (34 mg, 0.132 mmol) to afford the desired product (51 mg, 86%) as a light yellow solid: ESI MS m/z 538 [C30H33F2N3O4+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-270e0ca286a34b9c9924bd71b0ecd62d |
| Source note | uspto-grants-2015_09 |