HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol → HCID 68091923, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol | HCID 17750230 | — |
| Reactant | HCID 68091878 | HCID 68091878 | — |
| Product | HCID 68091923 | HCID 68091923 | 43.4% |
Reaction Steps
Following general procedure F, tert-butyl 4-{[6-bromo-3-(cyclopropanecarbonyl)quinolin-4-ylamino]methyl}piperidine-1-carboxylate (55 mg, 0.110 mmol) was reacted with 2-chloro-6-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (46 mg, 0.165 mmol) to afford the desired product (27 mg, 43%) as a yellow solid: ESI MS m/z 567 [C31H36ClN3O5+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-d349ecf0946a4faf8ae014d30f52b59b |
| Source note | uspto-grants-2015_09 |