HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol → HCID 178450292, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol | HCID 57655406 | — |
| Reactant | HCID 178450270 | HCID 178450270 | — |
| Product | HCID 178450292 | HCID 178450292 | 118.6% |
Reaction Steps
Following general procedure D, tert-butyl trans-4-(6-bromo-3-isobutyrylquinolin-4-ylamino)cyclohexylcarbamate (49 mg, 0.100 mmol) was reacted with 2,6-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (58 mg, 0.227 mmol) to afford the crude product (64 mg) as an off-white solid: ESI MS m/z 540 [C30H35F2N3O4+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-3bebbda20db54a64ae0fd11954b737b3 |
| Source note | uspto-grants-2015_09 |