HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol → HCID 178467113, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol | HCID 66716079 | — |
| Reactant | HCID 178467071 | HCID 178467071 | — |
| Product | HCID 178467113 | HCID 178467113 | 72% |
Reaction Steps
Following general procedure D, tert-butyl (trans-4-((3-acetyl-6-bromoquinolin-4-yl)amino)cyclohexyl)carbamate (46 mg, 0.10 mmol) was reacted with 2-chloro-6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (41 mg, 0.15 mmol) to afford the desired product (38 mg, 72%) as a light brown solid. ESI MS m/z 528 [C28H31ClFN3O4+H]+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-5eb45ebdfaf64f108aaedcc42b9bcde0 |
| Source note | uspto-grants-2015_09 |