HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol → HCID 86692984, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol | HCID 66715127 | — |
| Reactant | HCID 68092004 | HCID 68092004 | — |
| Product | HCID 86692984 | HCID 86692984 | 100.2% |
Reaction Steps
Following general procedure F, tert-butyl 4-{5-[6-bromo-3-(cyclopropanecarbonyl)quinolin-4-ylamino]pyridin-2-yl}piperazine-1-carboxylate (65 mg, 0.118 mmol) was reacted with 2,6-dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (51 mg, 0.177 mmol) to afford the crude product (75 mg) as an orange solid: ESI MS m/z 634 [C33H33C12N5O4+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-495db9c7969e4fc99dbe78dec3311632 |
| Source note | uspto-grants-2015_09 |