HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol → HCID 178453637, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol | HCID 66715127 | — |
| Reactant | HCID 178453636 | HCID 178453636 | — |
| Product | HCID 178453637 | HCID 178453637 | 80.7% |
Reaction Steps
Following general procedure F, tert-butyl {trans-4-[6-bromo-3-(cyclopropanecarbonyl)quinolin-4-ylamino]cyclohexyl}methylcarbamate (62 mg, 0.123 mmol) was reacted with 2,6-dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (53 mg, 0.185 mmol) to afford the crude product (58 mg) as a yellow solid: ESI MS m/z 584 [C31H35Cl2N3O4+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-b80fbbe7f53644ccada5ca4ece24c31b |
| Source note | uspto-grants-2015_09 |