HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol → HCID 178487411, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol | HCID 17750230 | — |
| Reactant | HCID 178453636 | HCID 178453636 | — |
| Product | HCID 178487411 | HCID 178487411 | 126.1% |
Reaction Steps
Following general procedure F, tert-butyl {trans-4-[6-bromo-3-(cyclopropanecarbonyl)quinolin-4-ylamino]cyclohexyl}methylcarbamate (65 mg, 0.123 mmol) was reacted with 2-chloro-6-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (55 mg, 0.185 mmol) to afford the crude product (90 mg) as a yellow-green solid: ESI MS m/z 580 [C32H38ClN3O5+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-240d63a82bf84d5aba04d80846a3bee2 |
| Source note | uspto-grants-2015_09 |