HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol → HCID 178487417, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol | HCID 17750230 | — |
| Reactant | HCID 178486048 | HCID 178486048 | — |
| Product | HCID 178487417 | HCID 178487417 | 114.9% |
Reaction Steps
Following general procedure F, tert-butyl {trans-4-[6-bromo-3-(cyclopropanecarbonyl)quinolin-4-ylamino]cyclohexyl}(methyl)carbamate (68 mg, 0.135 mmol) was reacted with 2-chloro-6-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (58 mg, 0.203 mmol) to afford the crude product (90 mg) as a brown oil: ESI MS m/z 580 [C32H38ClN3O5+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-de49f9e14d7a4e96be6e75501220a162 |
| Source note | uspto-grants-2015_09 |