HCID 13900588, compound → HCID 178488324, compound

HRID 2272035Notes

Reaction equation

HRID 2272035 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH3:13][O:14][C:15]1[C:20]2[C@@H:21]3[C@H:26]([CH2:27][CH2:28][C:19]=2[CH:18]=[CH:17][CH:16]=1)[NH:25][CH2:24][CH2:23][CH2:22]3>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([N:25]3[C@@H:26]4[C@@H:21]([C:20]5[C:15]([O:14][CH3:13])=[CH:16][CH:17]=[CH:18][C:19]=5[CH2:28][CH2:27]4)[CH2:22][CH2:23][CH2:24]3)=[O:12])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 13900588HCID 13900588, compoundHCID 178524171HCID 178524171, compound

Product 1

HCID 178488324HCID 178488324, compoundYield 55%

Procedure

The title compound is prepared from 1H-benzoimidazole-5-carboxylic acid and cis-10-methoxy-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline following a procedure analogous to that described in Example 1. Yield: 55% of theory; LC (method 1): tR=2.67 min; Mass spectrum (ESI+): m/z=362 [M+H]+.

Sources & evidence

ORD record
ord-79610e2be9e14ea080b14c1894bd8881
Source dataset
uspto-grants-2015_09
Patent number
US09120769B2

Reaction notes

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