HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylindole-3-carboxylic acid → (cis-7-Methoxy-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl)-(1-methyl-1H-indol-3-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylindole-3-carboxylic acid | HCID 854040 | — |
| Reactant | cis-7-Methoxy-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinoline | HCID 86654085 | — |
| Product | (cis-7-Methoxy-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl)-(1-methyl-1H-indol-3-yl)-methanone | HCID 86654119 | 82% |
Reaction Steps
The title compound is prepared from 1-methyl-1H-indole-3-carboxylic acid and cis-7-methoxy-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline following a procedure analogous to that described in Example 1. Yield: 82% of theory; LC (method 1): tR=4.39 min; Mass spectrum (ESI+): m/z=375 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120769B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-d74acc15c9594f64bd6427f8416545aa |
| Source note | uspto-grants-2015_09 |