HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluoro-4-hydroxybenzoic acid → HCID 86654120, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluoro-4-hydroxybenzoic acid | HCID 160456 | — |
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Reactant | (4aS,10bR)-1,2,3,4,4a,5,6,10b-Octahydrobenzo[f]quinoline | HCID 12327022 | — |
| Product | HCID 86654120 | HCID 86654120 | 40% |
Reaction Steps
The title compound is prepared from 3-fluoro-4-hydroxy-benzoic acid and cis-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline following a procedure analogous to that described in Example 1 [2-(7-aza-1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexa-fluorophosphate is used]. Yield: 40% of theory; LC (method 4): tR=1.94 min; Mass spectrum (ESI+): m/z=326 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120769B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-68ce0b28145646aa8f015bc3b7af2fec |
| Source note | uspto-grants-2015_09 |