HCID 86654148, compound → HCID 178489685, compound

HRID 2272098Notes

Reaction equation

HRID 2272098 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH3:13][O:14][C:15]1[CH:35]=[CH:34][C:18]([CH2:19][C:20]2[C:25]3[C@@H:26]4[C@H:31]([CH2:32][CH2:33][C:24]=3[CH:23]=[CH:22][CH:21]=2)[NH:30][CH2:29][CH2:28][CH2:27]4)=[CH:17][CH:16]=1>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([N:30]3[C@@H:31]4[C@@H:26]([C:25]5[C:20]([CH2:19][C:18]6[CH:34]=[CH:35][C:15]([O:14][CH3:13])=[CH:16][CH:17]=6)=[CH:21][CH:22]=[CH:23][C:24]=5[CH2:33][CH2:32]4)[CH2:27][CH2:28][CH2:29]3)=[O:12])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 86654148HCID 86654148, compoundHCID 178524171HCID 178524171, compound

Product 1

HCID 178489685HCID 178489685, compoundYield 17%

Procedure

The title compound is prepared from 1H-benzoimidazole-5-carboxylic acid and cis-10-(4-methoxy-benzyl)-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline following a procedure analogous to that described in Example 1. Yield: 17% of theory; LC (method 1): tR=3.21 min; Mass spectrum (ESI+): m/z=452 [M+H]+.

Sources & evidence

ORD record
ord-537bdb2c40914cf88f714588979f3442
Source dataset
uspto-grants-2015_09
Patent number
US09120769B2

Reaction notes

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