HCID 86654150, compound → HCID 178426068, compound

HRID 2272099Notes

Reaction equation

HRID 2272099 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH3:13][C:14]1([CH3:28])[CH2:23][C@H:22]2[C@H:17]([CH2:18][CH2:19][CH2:20][NH:21]2)[C:16]2[CH:24]=[CH:25][CH:26]=[CH:27][C:15]1=2>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([N:21]3[C@@H:22]4[C@@H:17]([C:16]5[CH:24]=[CH:25][CH:26]=[CH:27][C:15]=5[C:14]([CH3:28])([CH3:13])[CH2:23]4)[CH2:18][CH2:19][CH2:20]3)=[O:12])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 86654150HCID 86654150, compoundHCID 178524171HCID 178524171, compound

Product 1

HCID 178426068HCID 178426068, compoundYield 58%

Procedure

The title compound is prepared from 1H-benzoimidazole-5-carboxylic acid and cis-6,6-dimethyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline following a procedure analogous to that described in Example 1. Yield: 58% of theory; LC (method 1): tR=2.84 min; Mass spectrum (ESI+): m/z=360 [M+H]+.

Sources & evidence

ORD record
ord-0a23e1a14dfd44c29c5adc399629cf22
Source dataset
uspto-grants-2015_09
Patent number
US09120769B2

Reaction notes

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