HCID 86654075, compound → HCID 178492459, compound

HRID 2272102Notes

Reaction equation

HRID 2272102 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH3:13][O:14][C:15]1[CH:35]=[CH:34][C:18]([O:19][C:20]2[CH:33]=[CH:32][C:23]3[C@@H:24]4[C@H:29]([CH2:30][CH2:31][C:22]=3[CH:21]=2)[NH:28][CH2:27][CH2:26][CH2:25]4)=[CH:17][CH:16]=1>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([N:28]3[C@@H:29]4[C@@H:24]([C:23]5[CH:32]=[CH:33][C:20]([O:19][C:18]6[CH:17]=[CH:16][C:15]([O:14][CH3:13])=[CH:35][CH:34]=6)=[CH:21][C:22]=5[CH2:31][CH2:30]4)[CH2:25][CH2:26][CH2:27]3)=[O:12])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 86654075HCID 86654075, compoundHCID 178524171HCID 178524171, compound

Product 1

HCID 178492459HCID 178492459, compoundYield 72%

Procedure

The title compound is prepared from 1H-benzoimidazole-5-carboxylic acid and cis-8-(4-methoxy-phenoxy)-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline following a procedure analogous to that described in Example 1. Yield: 72% of theory; LC (method 1): tR=3.16 min; Mass spectrum (ESI+): m/z=454 [M+H]+.

Sources & evidence

ORD record
ord-60783b2cf9944611b92beef63c74c595
Source dataset
uspto-grants-2015_09
Patent number
US09120769B2

Reaction notes

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