HCID 67195150, compound → HCID 178509451, compound

HRID 2272103Notes

Reaction equation

HRID 2272103 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH2:13]1[C@@H:22]2[C@H:17]([CH2:18][CH2:19][C:20]3[CH:26]=[CH:25][C:24]([C:27]#[N:28])=[CH:23][C:21]=32)[NH:16][CH2:15][CH2:14]1>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([N:16]3[C@@H:17]4[C@H:22]([C:21]5[CH:23]=[C:24]([C:27]#[N:28])[CH:25]=[CH:26][C:20]=5[CH2:19][CH2:18]4)[CH2:13][CH2:14][CH2:15]3)=[O:12])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 67195150HCID 67195150, compoundHCID 178524171HCID 178524171, compound

Product 1

HCID 178509451HCID 178509451, compoundYield 18%

Procedure

The title compound is prepared from 1H-benzoimidazole-5-carboxylic acid and trans-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline-9-carbonitrile following a procedure analogous to that described in Example 1. Yield: 18% of theory; LC (method 1): tR=2.49 min; Mass spectrum (ESI+): m/z=357 [M+H]+.

Sources & evidence

ORD record
ord-9b9f0a6a870a4ad0b9c0b5f81f879e88
Source dataset
uspto-grants-2015_09
Patent number
US09120769B2

Reaction notes

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