反应详情

Commercially available 4-methoxy-2-nitrophenol (1 g, 5.9 mmol), a compound of formula (C) was dissolved in 10 mL of methanol, and then 10% Pd/C was added to the mixture. The mixture was hydrogenated in a Parr™ shaker at 30 psi until consumption of hydrogen stopped. The mixture was filtered through Celite and concentrated, to yield 2-amino-4-methoxyphenol a compound of formula (d), which was used without further purification.

1. customThe mixture was hydrogenated in a Parr™ shaker at 30 psi until consumption of hydrogen
2. filtrationThe mixture was filtered through Celite
3. concentrationconcentrated