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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 227247Generated: October 25, 2026

Hydrochloric Acid → 1,4-Diazepan-2-one hydrochloride

https://huagongshe.com/reaction/227247

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactanttert-Butyl 3-oxo-1,4-diazepane-1-carboxylateHCID 21962087—
Solvent1,4-DioxaneHCID 31275—
Product1,4-Diazepan-2-one hydrochlorideHCID 23447544—

Reaction Steps

Compound from Step B was treated with 4 N hydrogen chloride in dioxane at ambient temperature for 2.5 h. Concentration gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07560455B2
Source datasetuspto-grants-2009_07
ORD IDord-9334e80c14c045b58a60d9f0a1165788
Source noteuspto-grants-2009_07