1-Bromo-3-methoxypropane → Methyl 5-((4-cyanophenyl)(3-methoxypropyl)amino)-3-methyl-5-oxopentanoate

HRID 2272565Notes

Reaction equation

HRID 2272565 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10](=[O:19])[CH2:11][CH:12]([CH3:18])[CH2:13][C:14]([O:16][CH3:17])=[O:15])=[CH:5][CH:4]=1)#[N:2].Br[CH2:21][CH2:22][CH2:23][O:24][CH3:25]>>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([N:9]([CH2:21][CH2:22][CH2:23][O:24][CH3:25])[C:10](=[O:19])[CH2:11][CH:12]([CH3:18])[CH2:13][C:14]([O:16][CH3:17])=[O:15])=[CH:7][CH:8]=1)#[N:2]

Participants

3

Reactant 2

HCID 5245511-Bromo-3-methoxypropaneHCID 86729724Methyl 5-(4-cyanophenylamino)-3-methyl-5-oxopentanoate

Product 1

HCID 86729727Methyl 5-((4-cyanophenyl)(3-methoxypropyl)amino)-3-methyl-5-oxopentanoate

Procedure

Using methyl 5-(4-cyanophenylamino)-3-methyl-5-oxopentanoate and 1-bromo-3-methoxypropane, and by the reaction and purification in the same manner as in the method described in Step 2 of Example 8, methyl 5-((4-cyanophenyl)(3-methoxypropyl)amino)-3-methyl-5-oxopentanoate was obtained.

Workup

  1. customby the reaction and purification in the same manner as in the method

Sources & evidence

ORD record
ord-043dc571fc384a3d878c596a92e637d9
Source dataset
uspto-grants-2015_09
Patent number
US09120776B2

Reaction notes

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