3-((tert-Butoxycarbonyl)amino)-2-methylpropanoic acid → HCID 86729763, compound

HRID 2272606Notes

Reaction equation

HRID 2272606 reaction equation
[C:1]([O:5][C:6]([NH:8][CH2:9][CH:10]([CH3:14])[C:11]([OH:13])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH2:15]([N:17]1[C:29]2[CH:28]=[CH:27][C:26]([CH2:30][NH2:31])=[CH:25][C:24]=2[C:23]2[C:18]1=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH3:16]>>[CH2:15]([N:17]1[C:29]2[CH:28]=[CH:27][C:26]([CH2:30][NH:31][C:11](=[O:13])[CH:10]([CH3:14])[CH2:9][NH:8][C:6](=[O:7])[O:5][C:1]([CH3:2])([CH3:3])[CH3:4])=[CH:25][C:24]=2[C:23]2[C:18]1=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH3:16]

Participants

3

Reactant 2

HCID 41926403-((tert-Butoxycarbonyl)amino)-2-methylpropanoic acidHCID 10944107(9-ethylcarbazol-3-yl)methanamine

Product 1

HCID 86729763HCID 86729763, compound

Procedure

Using 3-((tert-butoxycarbonyl)amino)-2-methylpropanoic acid and (9-ethyl-9H-carbazol-3-yl)methanamine, and by the reaction and purification in the same manner as in the method described in Step 1 of Example 36, tert-butyl (3-(((9-ethyl-9H-carbazol-3-yl)methyl)amino)-2-methyl-3-oxopropyl)carbamate was obtained.

Workup

  1. customby the reaction and purification in the same manner as in the method

Sources & evidence

ORD record
ord-a018146b202247ab9734497dcdf02b09
Source dataset
uspto-grants-2015_09
Patent number
US09120776B2

Reaction notes

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