HCID 62965032, compound → HCID 86729784, compound

HRID 2272629Notes

Reaction equation

HRID 2272629 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH:10][C:11](=[O:19])[CH2:12][CH:13]([CH3:18])[CH2:14][C:15]([OH:17])=O)[CH:5]=[CH:6][C:7]=1[C:8]#[N:9].[Cl:20][C:21]1[CH:29]=[C:28]2[C:24]([CH:25]=[CH:26][N:27]2[CH3:30])=[CH:23][C:22]=1[NH2:31]>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:10][C:11](=[O:19])[CH2:12][CH:13]([CH3:18])[CH2:14][C:15]([NH:31][C:22]2[CH:23]=[C:24]3[C:28](=[CH:29][C:21]=2[Cl:20])[N:27]([CH3:30])[CH:26]=[CH:25]3)=[O:17])[CH:5]=[CH:6][C:7]=1[C:8]#[N:9]

Participants

3

Reactant 2

HCID 62965032HCID 62965032, compoundHCID 84657678HCID 84657678, compound

Product 1

HCID 86729784HCID 86729784, compound

Procedure

Using 5-(3-chloro-4-cyanophenylamino)-3-methyl-5-oxopentanoic acid and 6-chloro-1-methyl-1H-indol-5-amine, and by the reaction and purification in the same manner as in the method described in Step 2 of Example 3, the title compound was obtained.

Workup

  1. customby the reaction and purification in the same manner as in the method

Sources & evidence

ORD record
ord-137f02b5f5e044d998e13473ba6bb500
Source dataset
uspto-grants-2015_09
Patent number
US09120776B2

Reaction notes

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