Tert-butyl 2-fluoro-4-(2-(methylamino)-3-nitropyridin-4-yloxy)phenylcarbamate → HCID 67361368, 화합물

HRID 2272685노트

반응식

HRID 2272685 반응식
[F:1][C:2]1[CH:7]=[C:6]([O:8][C:9]2[CH:14]=[CH:13][N:12]=[C:11]([NH:15][CH3:16])[C:10]=2[N+:17]([O-])=O)[CH:5]=[CH:4][C:3]=1[NH:20][C:21](=[O:27])[O:22][C:23]([CH3:26])([CH3:25])[CH3:24]>C(O)C.[Pd]>[NH2:17][C:10]1[C:11]([NH:15][CH3:16])=[N:12][CH:13]=[CH:14][C:9]=1[O:8][C:6]1[CH:5]=[CH:4][C:3]([NH:20][C:21](=[O:27])[O:22][C:23]([CH3:25])([CH3:26])[CH3:24])=[C:2]([F:1])[CH:7]=1

참가 물질

4

반응물 1

HCID 57507628Tert-butyl 2-fluoro-4-(2-(methylamino)-3-nitropyridin-4-yloxy)phenylcarbamate

생성물 1

HCID 67361368HCID 67361368, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

Tert-butyl 2-fluoro-4-(2-(methylamino)-3-nitropyridin-4-yloxy)phenylcarbamate (5.3 mg, 14 mmol) was dissolved in absolute ethanol (600 mL) and hydrogenated on a 10% Pd/C cartridge through an H-Cube apparatus, to give the title compound as a yellow solid.

출처 및 근거

ORD 기록
ord-2f2340dc87904b219424b54d4fa82481
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09120789B2

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