Triphenylphosphine → HCID 57755946, compound

Participants

Reaction Steps

Under atmosphere of argon, a solution of methyl (3-hydroxy-4-methylphenyl)acetate (1.00 g) in methylene chloride (22 mL) was added by 2-{5-ethyl-2-[4-(trifluoromethoxy)phenyl]-1,3-oxazol-4-yl}ethanol (2.00 g), triphenylphosphine (2.18 g) and 1,1′-(azodicarbonyl)dipiperidine (2.10 g) and stirred overnight at room temperature. The reaction mixture was concentrated and the obtained residue was purified by column chromatography on silica gel (hexane:ethyl acetate=4:1) to give the title compound (2.38 g) having the following physical data.

Provenance & Evidence