tert-Butyl 3-(((methylsulfonyl)oxy)methyl)piperidine-1-carboxylate → HCID 67451375, compound

HRID 2272926Notes

Reaction equation

HRID 2272926 reaction equation
[C:1]1(=[O:15])[C:14]2[N:6]([N:7]=[C:8]3[C:13]=2[CH:12]=[CH:11][CH:10]=[CH:9]3)[CH2:5][CH2:4][CH2:3][NH:2]1.CS(O[CH2:21][CH:22]1[CH2:27][CH2:26][CH2:25][N:24]([C:28]([O:30][C:31]([CH3:34])([CH3:33])[CH3:32])=[O:29])[CH2:23]1)(=O)=O>>[O:15]=[C:1]1[C:14]2[N:6]([N:7]=[C:8]3[C:13]=2[CH:12]=[CH:11][CH:10]=[CH:9]3)[CH2:5][CH2:4][CH2:3][N:2]1[CH2:21][CH:22]1[CH2:27][CH2:26][CH2:25][N:24]([C:28]([O:30][C:31]([CH3:32])([CH3:34])[CH3:33])=[O:29])[CH2:23]1

Participants

3

Reactant 2

HCID 22647269tert-Butyl 3-(((methylsulfonyl)oxy)methyl)piperidine-1-carboxylateHCID 67450989HCID 67450989, compound

Product 1

HCID 67451375HCID 67451375, compound

Procedure

The product was prepared using the method described in example 1d), using 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,2-b]indazol-1-one and tert-butyl 3-{[(metylsulphonyl)oxy]methyl}piperidine-1-carboxylate as reagents. Thus, 3.6 g of tert-butyl 3-[(1-oxo-4,5-dihydro-1H-[1,4]diazepino[1,2-b]indazol-2(3H)-yl)methyl]piperidine-1-carboxylate were obtained.

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-7c6121302a6c4bbabc44d1c098d58072
Source dataset
uspto-grants-2015_09
Patent number
US09120801B2

Reaction notes

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