2-Butene, 1,4-dibromo- → HCID 70663136, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of N-benzyloxycarbonylbenzylamine (50 g), 1,4-dibromo-2-butene (44 g) and NaH (10.7 g, 60% in oil) in 350 ml of DMF is stirred at 0° C. for 1 h and then at 25° C. for 3 h. The reaction mixture is subjected to aqueous workup and the residue obtained is purified by chromatography over SiO2. The title compound is obtained as an oil having characterization data as indicated below.

Provenance & Evidence