N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide → N-[4-(2-amino-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-phenyl]-methanesulfonamide

Participants

Reaction Steps

Reaction of N-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-methanesulfonamide with 8-iodo-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamine analogously to general procedure 1 gives N-[4-(2-amino-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-phenyl]-methanesulfonamide which is reacted with 4-(4-chloro-phenyl)-morpholine to give the title compound as a solid.

Provenance & Evidence