HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-chloro-3,3-dimethyl-2,3-dihydro-1H-indol-2-one → 6-[8-(4-Methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamino]-3,3-dimethyl-1,3-dihydro-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-chloro-3,3-dimethyl-2,3-dihydro-1H-indol-2-one | HCID 58398957 | — |
| Reactant | 8-(4-Methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamine | HCID 117818394 | — |
| Product | 6-[8-(4-Methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamino]-3,3-dimethyl-1,3-dihydro-indol-2-one | HCID 117818180 | — |
Reaction Steps
8-(4-Methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamine, synthesized as described earlier, is coupled with 6-chloro-3,3-dimethyl-1,3-dihydro-indol-2-one under Buchwald Hartwig conditions using general procedure 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120804B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-4579303e3526469fa91464f51c029c69 |
| Source note | uspto-grants-2015_09 |