HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3S)-pyrrolidin-3-ol → 6-[8-((S)-3-hydroxy-pyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamino]-3,3-dimethyl-1,3-dihydro-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3S)-pyrrolidin-3-ol | HCID 2733874 | — |
| Reactant | 6-[8-((R)-3-hydroxy-pyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamino]-3,3-dimethyl-1,3-dihydro-indol-2-one | HCID 89767283 | — |
| Product | 6-[8-((S)-3-hydroxy-pyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamino]-3,3-dimethyl-1,3-dihydro-indol-2-one | HCID 89767125 | — |
Reaction Steps
The compound is synthesized using the procedure described for 6-[8-((R)-3-hydroxy-pyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamino]-3,3-dimethyl-1,3-dihydro-indol-2-one with (S)-3-hydroxy-pyrrolidin as nuceophile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120804B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-652cb10cdb7048938dc35bc373606f12 |
| Source note | uspto-grants-2015_09 |