2-Chloroadenosine → HCID 178453680, compound

Participants

Reaction Conditions

Reaction Steps

To a microwave tube containing 2-chloroadenosine (Aldrich Chemical) is added tert-butyl N-(2-aminoethyl)carbamate (AK Scientific, 10-fold molar excess). The mixture is heated in a microwave for 20 minutes at 120° C. under nitrogen. Workup of the reaction mixture, purification, and isolation of the title intermediate is carried out in a manner similar to that of Example 4, ROUTE 1, Step 3 used for Compound 16A.

Provenance & Evidence