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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2273095Generated: October 30, 2026

1-[(Tert-butoxy)carbonyl]piperidine-2-carboxylic acid → HCID 86731614, compound

https://huagongshe.com/reaction/2273095

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[(Tert-butoxy)carbonyl]piperidine-2-carboxylic acidHCID 581831—
Reactant(S)-Methyl 4-(1-aminoethyl)benzoate hydrochlorideHCID 57462942—
ProductHCID 86731614HCID 8673161497.9%

Reaction Steps

The title compound (D4) (1.95 g) was prepared according to the general procedure for amides preparation starting from 1-(tert-butoxycarbonyl)piperidine-2-carboxylic acid (1.17 g, available from Sigma Aldrich #495875), and (S)-methyl 4-(1-aminoethyl)benzoate hydrochloride (1.1 g, for preparation see published International Patent application WO 2005/105733). Reaction time: 18 hrs.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09120824B2
Source datasetuspto-grants-2015_09
ORD IDord-597d9a8861604f08aeaefcb476c319f3
Source noteuspto-grants-2015_09