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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2273097Generated: October 30, 2026

(2R)-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid → HCID 86731616, compound

https://huagongshe.com/reaction/2273097

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2R)-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acidHCID 688022—
Reactant(S)-Methyl 4-(1-aminoethyl)benzoate hydrochlorideHCID 57462942—
ProductHCID 86731616HCID 8673161693.2%

Reaction Steps

The title compound (D7) (815 mg) was prepared according to the general procedure for amides preparation starting from (R)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid (500 mg, available from Sigma Aldrich #433818), and (S)-methyl 4-(1-aminoethyl)benzoate hydrochloride (501 mg). Reaction time: 18 hrs

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09120824B2
Source datasetuspto-grants-2015_09
ORD IDord-8b41f3f17fe540f490313dbdc4bd0830
Source noteuspto-grants-2015_09