HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 86731617, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-(Bromomethyl)-3-(trifluoromethyl)benzene | HCID 123061 | — |
| Reactant | Cis-4-Hydroxy-D-Proline | HCID 440014 | — |
| Product | HCID 86731617 | HCID 86731617 | — |
Reaction Steps
The title compound (D8) (1.02 g) was prepared according to the general procedure for substituted benzyl amines preparation starting from cis-4-Hydroxy-D-proline (4.0 g; available from Aldrich#H5877) and 3-(Trifluoromethyl)benzyl bromide (9.37 ml). (Na2CO3: 2.5 eq; Reaction time: 24 hrs; 60° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120824B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-dcebb9053d214d4280a3dc64d9861567 |
| Source note | uspto-grants-2015_09 |