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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2273104Generated: October 31, 2026

Lithium Hydroxide → HCID 86731620, compound

https://huagongshe.com/reaction/2273104

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 86731617HCID 86731617—
ProductHCID 86731620HCID 86731620—

Reaction Steps

The title compound (D15) (16 mg) was prepared according to the general procedure for esters hydrolysis starting from (2R,4R)-3-(trifluoromethyl)benzyl 4-hydroxy-1-(3-(trifluoromethyl)benzyl)pyrrolidine-2-carboxylate (D8) (50 mg). (LiOH: 2 eq; Reaction time: 4 hrs).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09120824B2
Source datasetuspto-grants-2015_09
ORD IDord-5e409067e8a44c49ac6c4d34d6dddfbc
Source noteuspto-grants-2015_09