HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 71204753, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | m-Xylyl bromide | HCID 12099 | — |
| Reactant | HCID 71204683 | HCID 71204683 | — |
| Product | HCID 71204753 | HCID 71204753 | 71.6% |
Reaction Steps
The title compound (D24) (48 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from methyl 4-((S)-1-((R)-piperidine-2-carboxamido)ethyl)benzoate (D12) (50 mg, 0.17 mmol) and 3-methylbenzyl bromide (0.046 ml, 0.34 mmol). (Na2CO3: 2.5 eq; reaction time: 3 hrs; 60° C.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120824B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-7f2b1bdbb24e4dfb829f84e8f4cca7c6 |
| Source note | uspto-grants-2015_09 |