HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 71204721, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | m-Xylyl bromide | HCID 12099 | — |
| Reactant | HCID 71204726 | HCID 71204726 | — |
| Product | HCID 71204721 | HCID 71204721 | 43.8% |
Reaction Steps
The title compound (D33) (30 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from methyl 4-((S)-1-((R)-pyrrolidine-2-carboxamido)ethyl)benzoate (D14) (50 mg, 0.18 mmol) and 3-methylbenzyl bromide (0.05 ml, 0.36 mmol). (Na2CO3: 2.5 eq; reaction time: 5 hrs; 70° C.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120824B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-93b56cbeb5c9441682a90b433f24bd43 |
| Source note | uspto-grants-2015_09 |