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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2273120Generated: November 1, 2026

Methyl 4-(1-aminocyclopropyl)benzoate hydrochloride → HCID 71186561, compound

https://huagongshe.com/reaction/2273120

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(1-aminocyclopropyl)benzoate hydrochlorideHCID 66824369—
ReactantHCID 86731620HCID 86731620—
ProductHCID 71186561HCID 7118656142.3%

Reaction Steps

The title compound (D35) (10.3 mg) was prepared according to the general procedure for amides preparation starting from lithium (2R,4R)-4-hydroxy-1-(3-(trifluoromethyl)benzyl)pyrrolidine-2-carboxylate (D15) (11.7 mg, 0.054 mmol) and methyl 4-(1-aminocyclopropyl)benzoate hydrochloride (27.2 mg, 0.054 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09120824B2
Source datasetuspto-grants-2015_09
ORD IDord-af2c36f972b84feebeaadc5f2c895d59
Source noteuspto-grants-2015_09