HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium hydroxide, monohydrate → HCID 71186455, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | HCID 71204692 | HCID 71204692 | — |
| Product | HCID 71186455 | HCID 71186455 | — |
Reaction Steps
The title compound (E20) (50 mg) was prepared according to the general procedure for esters hydrolysis starting from methyl 4-((S)-1-((2R,4S)-4-fluoro-1-(3-(trifluoromethyl)benzyl)pyrrolidine-2-carboxamido)ethyl)benzoate (D37) (67.3 mg). (LiOH H2O: 2 eq; reaction time: 18 hrs)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120824B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-8d9caa6374094d0a9f0817a0f9a8973c |
| Source note | uspto-grants-2015_09 |