HCID 58333155, compound → HCID 58964468, compound

Participants

Reaction Steps

To a solution of 2-allyloxy-2-trifluoromethyl-but-3-enoic acid ethyl ester (2.15 g, see above) in CH2Cl2 (100 mL) at room temperature was added Grubbs catalyst 2nd generation (Aldrich) (67 mg). The resulting mixture was stirred for 18 h at room temperature. The reaction mixture was then filtered through a plug of Celite® and silica gel, rinsed with EtOAc and then concentrated to yield the title compound as a yellow oil.

Provenance & Evidence